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C3M
Le Centre Méditerranéen de Médecine Moléculaire créé en 2008 résulte de la volonté de rassembler des équipes toutes désireuses d’un fort rapprochement avec la clinique et soucieuses d’améliorer leurs interactions. L’implantation du Centre au sein de l’Hôpital de l’Archet, facilite le transfert de la clinique vers la recherche fondamentale et vice versa. Le C3M comprend 13 équipes (site web https://www.c3m-nice.fr/) regroupant 175 personnes, réparties en 3 axes de recherche : - Prolifération, morts cellulaires, différenciation et cancer, - Maladies métaboliques et - Infection et réponses inflammatoires. Le C3M dispose d’une importante plateforme d’imagerie cellulaire et de cytométrie labellisée IBISA.
Derniers dépôts
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Christopher Montemagno, Arnaud Jacquel, Charlotte Pandiani, Olivia Rastoin, Rosie Dawaliby, et al.. Unveiling CXCR2 as a promising therapeutic target in renal cell carcinoma: exploring the immunotherapeutic paradigm shift through its inhibition by RCT001. Journal of experimental & clinical cancer research, 2024, 43, pp.86. ⟨10.1186/s13046-024-02984-2⟩. ⟨hal-04571570⟩
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Claire Muller, Victorine Lacroix-Malgras, Jérôme Kluza, William Laine, Yonca Güler, et al.. The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitors. Cancer Cell International, 2024, 24 (1), pp.132. ⟨10.1186/s12935-024-03319-z⟩. ⟨hal-04564424⟩
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Bi Goré Oscar Tchan, Solange Kakou-Ngazoa, Sylveste Dizoe, Nassim Hammoudi, Ghiles Grine, et al.. Mycobacterium ulcerans-Bordetella trematum chronic tropical cutaneous ulcer: A four-case series, Côte d’Ivoire. PLoS Neglected Tropical Diseases, 2023, 17 (12), pp.e0011413. ⟨10.1371/journal.pntd.0011413⟩. ⟨hal-04509454⟩
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Rodolphe Anty, Marie Morvan, Maëna Le Corvec, Clémence Canivet, Stéphanie Patouraux, et al.. The mid-infrared spectroscopy: A novel non-invasive diagnostic tool for NASH diagnosis in severe obesity. JHEP Reports Innovation in Hepatology, 2019, 1 (5), pp.361-368. ⟨10.1016/j.jhepr.2019.09.005⟩. ⟨hal-04009608⟩
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Pierre Leclère, Déborah Rousseau, Stéphanie Patouraux, Sophie Guérin, Stéphanie Bonnafous, et al.. MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice. Scientific Reports, 2020, 10 (1), pp.12139. ⟨10.1038/s41598-020-69085-w⟩. ⟨hal-02909860⟩
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Mots clés
Metformin
Monocytes
Cell biology
Breast cancer
Mechanotransduction
Migration
Adipocytes
Glucose
Female
Leukemia
Transduction
Diagnosis
Inflammation
UPR
Cells
AML
Genetic Vectors
Resistance
Cirrhosis
Steatosis
Metabolism
Genetic Therapy
ER stress
Lentivirus
Epidemiology
HEK293 Cells
Middle Aged
Genomics
Fibrosis
Genetic
Mice
Aged
Bacteremia
Antiviral Agents
Hepatitis C
Actin cytoskeleton
Prognosis
Macrophages
Autophagy
Immunometabolism
Chronic hepatitis C
Chronic
Humans
Bariatric surgery
Epigenetics
Carcinoma
Immunotherapy
Obesity
Diabetes
Cell proliferation
DDR
Prostate cancer
Hepatocellular carcinoma
Macrophage
Cohort Studies
Quality
Gene Expression Regulation
Apoptosis
Cancer
Cell Line
Lymphocyte Activation
France
NAFLD
Liver
Hypoxia
Chronic myeloid leukemia
Liver Cirrhosis
Adipose tissue
Stress
Targeted therapies
NASH
IRE1α
Cell Proliferation
B-Lymphocytes
Cultured
Cell death
Leishmania
Rac1
Métabolisme
COVID-19
Foie
Innate immunity
MITF
Glutamine
Aging
Melanoma
Adult
Quality of Life
Membrane Glycoproteins
Glycolysis
Atherosclerosis
Male
Inflammasome
Extracellular matrix
Angiogenesis
Animals
Apoptose
Mélanome
Binge eating disorder
Mitochondria